Santa Croce Vacations from $959
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Your Santa Croce Vacation
Our Santa Croce vacation packages are a fast and practical way to plan and reserve your next adventure. Uncover the true character of this unique neighborhood without the hassle of having to organize everything yourself. Some top nearby attractions to see during your trip to Santa Croce include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia can put your plans into action. Book your ultimate Santa Croce vacation now.
The Latest Santa Croce Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi
Historic Centre of Florence
$959
per person
Oct 22 - Oct 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,003 reviews)
The room was exceptionally clean, including the floor (white napkin test).
The staff was super friendly, and the check-in.check out quick.
The breakfast is simple, yet with there was a good choice of all you can eat items: toast with a choice of cold ham, mozzarella cheese, tomato slices, salame, ect, mini-pancakes. They also offer freshly-baked croissant fillable with assorted jam, creams etc, cakes, etc. Plus, fresh squeezed orange juice, and other juices, and all type of coffees.
The hotel was well located (close to the Uffizi Galley) and the Arno river (Ponte Vecchio).
Reviewed on Aug 10, 2026
Relais Uffizi, Tailor made Hotel
Historic Centre of Florence
$2,759
per person
Sep 21 - Sep 26
found 12 hours ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.2/10 Wonderful! (154 reviews)
While the bathrooms were clean I was very disappointed to see a stain on my bedsheets.
Reviewed on Aug 2, 2026
Eden Rock Resort
$1,638
per person
Oct 22 - Oct 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.8/10 Exceptional! (109 reviews)
This was a beautiful property about 10 mins away from Florence. You get the beauty of Tuscany without having to go too far. The hotel only has 12 rooms and everyone knows you by name. We traveled with 2 kids and the rooms were very spacious. Staff are wonderful, Onsite restaurant was great. Views were breathtaking. We didn't have a car, and the hotel was able to help us with cabs easily. Service was excellent and we would highly recommend this hotel!
Reviewed on Jul 18, 2026
The Moon Boutique Hotel & Spa
Historic Centre of Florence
$1,313
per person
Oct 23 - Oct 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (577 reviews)
Everything was great! Friendly staff, clean and comfortable rooms, and a relaxing atmosphere overall. We really enjoyed our stay!
Reviewed on Aug 1, 2026
Where to stay in Santa Croce
Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Duomo
Framed by a magnificent cathedral and charming streets lined with churches and restaurants, this neighborhood rests at the very heart of Florence.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
Santa Maria Novella
Spend some time in an attractive neighborhood close to the city center that encompasses ancient buildings and churches and a large park of outstanding beauty.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Croce Hotel Deals
Plaza Hotel Lucchesi
Lungarno Della Zecca Vecchia 38 Florence FI
Fully refundableReserve now, pay when you stay
$228 nightly
$267 total
Aug 18 - Aug 19
Total with taxes and fees
FH55 Grand Hotel Mediterraneo
Lungarno del Tempio, 44 Florence FI
Fully refundableReserve now, pay when you stay
$99 nightly
$125 total
Aug 16 - Aug 17
Total with taxes and fees
8.2/10 Very Good! (1,006 reviews)
"Location was not too far from the main parts but far enough to avoid crowds of the city. It looked like the room temperature cannot be controlled by the room thermostat It was centrally set to ~18C which during the day was perfect but at night, it felt cold. They provide 2 bottled water per day with ..."
Reviewed on Aug 9, 2026
Hotel Balestri
Piazza Mentana 7 Florence FI
Fully refundableReserve now, pay when you stay
$179 nightly
$213 total
Aug 18 - Aug 19
Total with taxes and fees
9.4/10 Exceptional! (1,004 reviews)
"We absolutely loved our stay here! Great location, beautiful room , the staff was great and the breakfast was excellent. Would highly recommend."
Reviewed on Aug 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Croce attractions
Piazza Santa Croce
8.8/10 (12 reviews)
Italy’s most famous soccer game takes place here once a year, but the square is better known as a nighttime hangout of choice for young people.
Basilica of Santa Croce
9.2/10 (3,079 reviews)
Glorious tombs mark the resting place of Michelangelo, Galileo and many other Italian greats in the largest Franciscan church in the world.
Teatro Verdi
9.0/10 (2 reviews)
Get tickets for a show at Teatro Verdi, a storied theater in Florence. Discover the acclaimed art scene and churches in this vibrant area.
Church of Sant'Ambrogio
9.0/10 (13 reviews)
After visiting Church of Sant'Ambrogio, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Mercato di Sant'Ambrogio
10.0/10 (1 review)
You can browse for the perfect souvenirs at Mercato di Sant'Ambrogio during your trip to Florence. Discover the fascinating museums and notable monuments in this vibrant area.
Casa Buonarroti
8.0/10 (3 reviews)
You can study the exhibits at Casa Buonarroti, a museum with a story of its own, during your trip to Florence. Discover the fascinating museums and notable monuments in this vibrant area.
National Central Library of Florence
Find out about the history of Florence when you take a trip to National Central Library of Florence. Discover the area's beautiful sunsets and stunning cathedral.
Palazzo dell'Antella
You can find out about the history of Florence with a trip to Palazzo dell'Antella. Discover the acclaimed art scene and churches in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$28
per adult
76% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
$82
per adult
98% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
$133
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.